Stupid Brits to jump on the folic acid bandwagon. Who cares if it gives people bowel cancer?

Because America does it, it must be OK, seems to be their reasoning. The article excerpted below says that the experts have found no evidence of harm from folates. They were not looking very hard. I can find plenty and I am only a desultory reader of the relevant literature. Note this recent expert comment about folates and bowel cancer:

"Other reasonable hypotheses about one-carbon metabolism and colorectal carcinogenesis, based on our current understanding of the biochemistry and underlying mechanisms, have also not been proven correct. In a recently published placebo-controlled randomized clinical trial among 1021 men and women with a recent history of colorectal adenoma, supplemental folic acid at 1 mg/d for up to 6 years did not reduce the incidence of subsequent colorectal adenomas and might have increased it."

WHOA! The folate that Americans get compulsorily added to their bread did no good and seems to have done harm?? And do we see a double blind controlled study contradicting epidemiological inferences?? Who would have believed it! They go on to admit that two animal studies have shown that folate INCREASES cancer. Aren't you glad that your government is dosing you up with the stuff and giving you no say in the matter?

The addition of folate to our bread is more and more looking like an iatrogenic disaster to come. I think I should note once again that a folate expert has reported that the addition of folate to bread seems to have caused an upsurge in bowel cancer among Americans.

Bread should be fortified with folic acid by law to cut the risk of birth defects, the Food Standards Agency decided yesterday. The FSA board, which was split on the issue when it was last discussed in 2002, decided unanimously to back a recommendation from its scientific advisers for mandatory fortification of flour or bread, whichever is the more practicable.

In the US, Canada and several other countries, mandatory fortification has already cut sharply birth defects such as spina bifida. But Britain has hung back because of doubts about possible side-effects, and fear that "compulsory medication" would cause a public outcry.

The recommendation will now go to ministers, who will decide whether to implement it. If they do they could face opposition in the House of Commons but will be able to cite a mass of evidence gathered by the FSA.

The mandatory fortification of bread would include regular white and brown bread, but not wholemeal, enabling objectors to opt out. It would also be accompanied by controls on food that are already fortified voluntarily by manufacturers, such as some breakfast cereals, to avoid any possibility of an overdose.

The FSA board was given a range of options to consider, including the present policy of advising women planning pregnancies to take folic acid supplements. But half of pregnancies are unplanned, and the advice does not reach women in lower social classes whose diets are the most likely to be deficient. It has had relatively little effect.....

Source


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